Special Fall Seminar: Current Controversies in Neuroscience and Behavior

 

 

PSB 4934 (undergraduates); PSB 7249 (grad students)

Tuesdays 4:05 p.m. – approximately 6:45 p.m., Room: Larsen 310

 

 

 

Instructor: Linda Hermer-Vazquez, Ph.D.

Office hours: Tues., 2 – 4 p.m., Rm. 322, Psychology Building

(352) 273-2172; lindahv@ufl.edu

 

 

 

Introduction: Scientific results acquired with new and advanced techniques for studying the nervous system are forcing a reconsideration of many long-held neuroscientific beliefs.  This course will explore several of those controversies, which will range across behavioral, systems, and molecular neuroscience.  In the introductory lecture on August 26th, 2008, Dr. H.-V. will review the main neuroscience concepts needed for success in the course.  At the next meeting, she will present more advanced neuroscience material covered in an assigned reading.  From then on, student teams will present review paper-based introductions to each controversy that we’ll cover, then more advanced articles leading to classroom debates.  Short write-ups of the assigned articles for each topic (a subset of the total number of articles presented) will be due the day they are covered in class.  Otherwise, students’ grades will be based entirely on classroom presentations and participation in discussions.

 

 

Grading:          40% -- classroom presentations

40% -- participation in classroom discussions

20% -- write-ups of articles for discussion

 

 

Introductory week: Aug. 26th, 2008

Review of basic neuroscience and neuroscientific study techniques

 

·         No articles or write-ups will be assigned for this meeting.

 

 

Sept. 2nd, 2008

1st period -- Review and discussion of local field potentials and the methods for multi-site, multi-electrode recording 

 

·         Assigned reading: Bullock, 1997: Signals and signs in the nervous system: the dynamic anatomy of electrical activity is probably information-rich.  PNAS 94 (1): 1-6.

 

2nd and 3rd periods -- Discussion of the classical view of motor coding. 

 

·         Assigned reading: Georgopoulos, 1995: Current issues in directional motor control.  TINS 18 (11): 506 – 510.  PDF

 

·         Presented articles: Georgopoulos, 1988, and Georgopoulos, 1995 (PDF above)

 

Sept. 9th, 2008

A newer and compelling, although still controversial, view of action representation in the cortex (periods 1-2)

 

·   Assigned reading: Graziano and Aflalo, 2007: Mapping behavioral repertoire onto the cortex.  Neuron 56: 239-251.  PDF

 

·   Presented articles: The assigned reading, plus Aflalo and Graziano, 2006 (PDF); and Aflalo and Graziano, 2007 (PDF)

 

·   Period 3 or period 1 of next meeting -- Recent articles contributing to the debate, and an overall discussion of the topic

 

·   Presented articles: Stark et al., 2007 (PDF) and Hatsoupolous et al., 2007 (PDF)

 

Sept. 16th, 2008

Action and imitation: How much of primate behavior can be explained by neural interactions with mirror neurons?

 

Assigned reading: Jackson and Decety, 2004: Motor cognition: A new paradigm to study self-other interactions.  Current Opinion in Neurobiology 14: 259-63.  (PDF)

 

More coming…

 

Sept. 23rd, 2008

The debate over mirror cells, language acquisition, and autism

 

Sept. 30th, 2008

What role(s) does the cerebellum play in cognition?

 

Oct. 7th, 2008

Mechanisms of SSRIs and traditional anti-psychotic drugs

 

Oct. 14th, 2008

Atypical anti-depressants and anti-psychotics: What’s known about how they work?

 

Oct. 21st, 2008

Catch-up day – YES, this class is mandatory!

 

Oct. 28th, 2008

What causes hallucinations in psychotic patients?

 

Nov. 4th, 2008

What causes hallucinations in users of LSD, psilocybin and peyote, and are the mechanisms similar to those seen in schizophrenics and psychotic depression patients?

 

Nov. 11th, 2008

Veteran’s Day – no class

 

Nov. 18th, 2008

Introduction to neural theories of decision-making

 

Nov. 25th, 2008

Multiple circuits, not limited to the PFC, involved in decisions to act

 

Dec. 2nd, 2008

Beyond the homunculus: Decision-making, attention and working memory

 

Dec. 8th, 2008

Do eating disorders and self-cutting involve an addictive component?